Sage reports
Full philosophy-of-medicine essays. Each report has a matching Coach page and a Surfer outline on Surfer. Cross-link these URLs from Store, Shore, and other lessons.
Beside Fuel · Circadian · Strength — Does not replace the ride pillars. Sections: Clean Line · Wipeout · The Kit.
Good Doctor
- Good Doctor hub Surfer Coach Sage
- Clean Line Surfer Coach Sage
- Philosophy of Medicine: Disease as chronic compensatory mode Surfer Coach Sage
- Aging: Loss of ATP generating capacity Surfer Coach Sage
- Mitochondrial Gate: Epigenetic reprogramming / plasticity gated by mitochondrial competence Coach Sage
- Warburg and Crabtree: acute and chronic compensation Sage
- Beauty: Beauty cues as readouts of cellular energy; mimics versus restoration (hypothesis) Sage
- Natural Intelligence: Biology as the original inference engine: free energy, Markov blankets, mitochondria as substrate (philosophy) Coach Sage
- Brown Fat: Engine capacity versus dashboard readings; nocturnal cardiac buffering (testable hypothesis) Coach Sage
- Neanderthal Extinction: Mitochondrial hypothesis: the complete replacement of maternal lineages, mitonuclear hybrid costs, climate-adapted mtDNA Coach Sage
Wipeouts
Cardiopulmonary
- Cardiac: Atherosclerosis as energy failure; NO flux manager / scar grammar Surfer Coach Sage
- Nitric Oxide: NO flux manager / scar grammar Sage
- Hypertension: Pressure as readout, resistance as scar: nitric oxide, endothelium, wall, kidney (hypothesis) Coach Sage
- Pulmonary: The lung as oxidizer organ: asthma, COPD, sleep apnea, lung cancer, infection, fibrosis (hypothesis) Coach Sage
- Heart Failure: Cardiomyopathy and heart failure as chronic energy starvation under sustained load (hypothesis) Coach Sage
- Arrhythmia: Electrophysiology: energy-dependent ion homeostasis (hypothesis) Sage
- Arterial and Venous Occlusions: Retinal artery and vein occlusions, NAION, and the same failure in heart, brain, and leg (hypothesis) Coach Sage
- Brown Fat: Engine capacity versus dashboard readings; nocturnal cardiac buffering (testable hypothesis) Coach Sage
- Kidney Disease: The kidney as an energy engine: mitochondria, nitric-oxide matching, diabetic and hypertensive kidney disease (hypothesis) Coach Sage
Dental
Dermatology
- Dermatology: Hair/skin as ATP mismatch Surfer Coach Sage
- Leprosy: Mycobacterium leprae and the dismantling of host mitochondria (hypothesis) · spiritual reading: Jesus and the leper Sage
- Skin Cancer Sage
Endocrinology and metabolism
- Endocrinology and metabolism Coach Sage
- Diabetes: Sequestration; water, water everywhere Surfer Coach Sage
- Obesity: Engine vs GLP-1 dashboard Surfer Coach Sage
- Thyroid / Temperature: Thermal chapter; thyroid as tempo governor; 24h temp curve Surfer Coach Sage
- Signals: Cell-signaling dysfunction; energy-signal cluster; NO matching nest Surfer Coach Sage
- Serotonin: Bioenergetic flux manager; oxygen/carbon matching (not a happiness molecule) Surfer Coach Sage
- Calcium: Bone as the dynamic reservoir, not a static scaffold (hypothesis) Sage
- Adenosine: Primary energy-stress signal; hormesis requires recovery (hypothesis) Sage
- Breast Cancer: Insulin receptors, high insulin, and fasting-mimicking and ketogenic diet trials alongside chemotherapy (hypothesis) Sage
- Brown Fat: Engine capacity versus dashboard readings; nocturnal cardiac buffering (testable hypothesis) Coach Sage
- Kidney Disease: The kidney as an energy engine: mitochondria, nitric-oxide matching, diabetic and hypertensive kidney disease (hypothesis) Coach Sage
- Liver Disease: The liver as the body's energy manager: zonation, alcohol and fructose, fatty liver, fibrosis (hypothesis) Coach Sage
Gastroenterology
- GI Surfer Coach Sage
- Ferritin: Iron sequestration as sentinel of bioenergetic integrity and redox coherence (hypothesis) Sage
- Autoimmune gastritis: Parietal energetics; ferritin as bioenergetic sentinel (hypothesis) Sage
- Forced Differentiation: Colon-cancer reversion: a forced phenotype is not a moved set point (commentary) Sage
- Colorectal Cancer Sage
- Liver Disease: The liver as the body's energy manager: zonation, alcohol and fructose, fatty liver, fibrosis (hypothesis) Coach Sage
Genetics
- Brain: Excerpt — neurodegeneration chapter Surfer Coach Sage
- Neurodevelopment: Autism and Down syndrome read as metabolic compensation Surfer Coach Sage
- Neanderthal Extinction: Mitochondrial hypothesis: the complete replacement of maternal lineages, mitonuclear hybrid costs, climate-adapted mtDNA Coach Sage
Hepatology
- Liver Disease: The liver as the body's energy manager: zonation, alcohol and fructose, fatty liver, fibrosis (hypothesis) Coach Sage
- Liver Cancer Sage
Infectious Disease
Chapter: Sage
- Viruses and Prions: Nested memory, energy-flux constraints, and compensatory locking (hypothesis) Sage
- Dental: Mouth as mitochondrial canary Surfer Coach Sage
- Immune: Excerpt — chapter in Philosophy Surfer Coach Sage
- Pulmonary: The lung as oxidizer organ: asthma, COPD, sleep apnea, lung cancer, infection, fibrosis (hypothesis) Coach Sage
- Leprosy: Mycobacterium leprae and the dismantling of host mitochondria (hypothesis) · spiritual reading: Jesus and the leper Sage
- mRNA Vaccine-Associated Cancer Relapse: Proteomic load, mitochondrial insufficiency, and Warburg-like rescue (hypothesis) Sage
- Lyme and Alpha-Gal Coach Sage
- POTS Sage
Nephrology
- Kidney Disease: The kidney as an energy engine: mitochondria, nitric-oxide matching, diabetic and hypertensive kidney disease (hypothesis) Coach Sage
- Kidney Cancer Sage
Neurology / brain
- Brain: Excerpt — neurodegeneration chapter Surfer Coach Sage
- Signals: Cell-signaling dysfunction; energy-signal cluster; NO matching nest Surfer Coach Sage
- Neurodevelopment: Autism and Down syndrome read as metabolic compensation Surfer Coach Sage
- Serotonin: Bioenergetic flux manager; oxygen/carbon matching (not a happiness molecule) Surfer Coach Sage
- Tau pathology: Phosphorylated tau and reverse electron transport as a self-reinforcing loop (hypothesis) Coach Sage
- Stroke and arterial occlusion Coach Sage
- Viruses and Prions: Nested memory, energy-flux constraints, and compensatory locking (hypothesis) Sage
Obstetrics and Gynecology
- Reproductive / infertility Surfer Coach Sage
- Childbirth planning Coach Sage
- Breast Cancer: Insulin receptors, high insulin, and fasting-mimicking and ketogenic diet trials alongside chemotherapy (hypothesis) Sage
Oncology
- Cancer: Energy crisis plus glycolytic selection Surfer Coach Sage
- Warburg and Crabtree: acute and chronic compensation Sage
- Forced Differentiation: Colon-cancer reversion: a forced phenotype is not a moved set point (commentary) Sage
- mRNA Vaccine-Associated Cancer Relapse: Proteomic load, mitochondrial insufficiency, and Warburg-like rescue (hypothesis) Sage
- Breast Cancer: Insulin receptors, high insulin, and fasting-mimicking and ketogenic diet trials alongside chemotherapy (hypothesis) Sage
- Colorectal Cancer Sage
- Skin Cancer Sage
- Retinoblastoma Coach Sage
- Kidney Cancer Sage
- Liver Cancer Sage
Ophthalmology
- Ophthalmology Coach Sage
- Eye: Excerpt — organ prototype Surfer Coach Sage
- Glaucoma: Lamina cribrosa energetics; nitric oxide in outflow; corollaries with hypertension (hypothesis) Sage
- Ocular surface (dry eye) Coach Sage
- Blue Eyes: Iris depigmentation as circadian entrainment optimization (hypothesis) Sage
- Retinitis Pigmentosa and Inherited Retinal Disease: Photoreceptor energy flux relative to load, embryologic lock-in, variable penetrance (hypothesis) Coach Sage
- Retinoblastoma Coach Sage
- Hypertension and Glaucoma Coach Sage
- Fuchs’ Dystrophy: Cornea: endothelial pump energy failure, cataract surgery as stress test, band keratopathy (hypothesis) Coach Sage
- Arterial and Venous Occlusions: Retinal artery and vein occlusions, NAION, and the same failure in heart, brain, and leg (hypothesis) Coach Sage
Rheumatology, inflammation and immunology
- Immune: Excerpt — chapter in Philosophy Surfer Coach Sage
- Warburg and Crabtree: acute and chronic compensation Sage
- Autoimmune gastritis: Parietal energetics; ferritin as bioenergetic sentinel (hypothesis) Sage
- Leprosy: Mycobacterium leprae and the dismantling of host mitochondria (hypothesis) · spiritual reading: Jesus and the leper Sage
- Viruses and Prions: Nested memory, energy-flux constraints, and compensatory locking (hypothesis) Sage
- Lyme and Alpha-Gal Coach Sage
Kit
MB, aspirin, sulindac, catecholamine modulators — education only; no dosing from Surfer. Board first (Fuel · Circadian · Strength); Kit last.
- Acetyl-L-carnitine Surfer Coach Sage
- Alpha-lipoic acid Surfer Coach Sage
- AREDS3 Surfer Coach Sage
- Aspirin Surfer Coach Sage
- Astaxanthin Surfer Coach Sage
- Broccoli sprouts Surfer Coach Sage
- Catecholamines Surfer Coach Sage
- CoQ10 Surfer Coach Sage
- DMSO Surfer Coach Sage
- Endocannabinoids Surfer Coach Sage
- Fewer double bonds Surfer Coach Sage
- GLP-1s / statins Surfer Coach Sage
- Grapefruit Surfer Coach Sage
- Methylene blue: Catalytic ETC shuttle; Strength / ETC+ Surfer Coach Sage
- NAD+ precursors Surfer Coach Sage
- PQQ Surfer Coach Sage
- Rapamycin Surfer Coach Sage
- Sulindac Surfer Coach Sage
The Shore
- The Shore: field, word, and love Surfer Coach Sage
- Living Water: under Fuel Surfer Sage
- Worship Sage
- First Light: under Circadian Surfer
- Sabbath and rest Sage
- Music as Temporal Coherence: under Circadian Sage
- Agape: under Strength Surfer Coach Sage
- Jesus and the leper Sage
- The miracles are spiritual Sage
- Strength as service Sage
- Death and heaven Sage
Ride pillars
- Fuel — Nested symbionts; animal fats/proteins; fermented MACs
- — Animal fats — Energy composition fin
- — HydroEye (membrane fork) — Fuel · GLA+EPA/DHA
- — Animal proteins — Substrate/signal fin
- — MAC / biota fuel — Fermented MACs & mushrooms
- — Toxins (jellyfish) — Sugars · seed oils · alcohol · THC · caffeine · environmental
- Circadian / Energy Phase — Time-structured energy management; four timing sub-pillars
- — Circadian Light — Metabolic hypothesis of light (sub-pillar)
- — Blue Eyes — Iris depigmentation as circadian entrainment optimization (hypothesis)
- — Circadian Temperature — Thermal timing sub-pillar (24h curve; thyroid tempo linked separately)
- — Brown Fat — Engine capacity versus dashboard readings; nocturnal cardiac buffering (testable hypothesis)
- — Circadian Hormesis timing — When of capacity stressors (upgrade from Movement; Strength owns program)
- — Circadian Fuel timing — When of substrate (Active vs Restore; Fuel pillar owns composition)
- Strength — Metabolic Hypothesis of Strength; Dual-Pathway week
- — Biogenesis — Mitochondrial density
- — Mitophagy — Mitochondrial quality / age
- — Strength-volume / hypertrophy — Tension → volume
- — ETC function — Electron-transport efficiency
See the notice at the top of this page. Working hypothesis, not medical advice.